Scientific Area: Stem cell biology, Bioengineering.
Project Title: ?Harnessing endothelial plasticity for therapeutic vascularization of ischemic tissues: a bioengineering approach?.
Workplans: The work will be carried out within the scope of Tasks 3 to 5 of the project. Specific goals include: 1) derive and characterize endothelial cells, mesenchymal cells and cardiomyocytes from induced pluripotent stem cells; 2) establish multi-cell 3D microtissues; 3) characterize the regeneration potential of microtissues in vitro and in vivo.
The drafts of the contract fellowship and the evaluation report are available at the i3S Research Fellowships Regulation, published at https://www.i3s.up.pt/job-opportunities.php
Admission Requirements: Mandatory requirements - candidates should hold a PhD degree in Biology, Bioengineering or related areas and less than 3 years of postdoctorate. Advanced knowledge in stem cell biology and cell/molecular biology techniques. Excellent English communication skills. Preferential requirements: knowledge on transcriptomics, and in vitro culture of endothelial cells and cardiomyocytes. Animal experimentation: Course in Laboratory Animals Science.
In the event the doctorate degree was awarded by a foreign higher education institution, said degree must comply with the provisions of Decree-Law no. 341/2007 of 12 October, and all formalities established therein must be complied with at the signature of contract.
The Doctorate beneficiary of this type of fellowship cannot exceed, with the conclusion of the fellowship contract, an accumulated period of three years under this type of scholarship, continuous or not continuously calculated. The calculation of the three years period considers also all the host entities to which the Doctorate has been linked to by a postdoctoral fellowship.
Legislation and other applicable regulations: Research Fellowship Holder Statute enacted by Law no. 40/2004 of August 18th, as amended; FCT Research Grants Regulation, approved by way of Regulation nr. 950/2019, published in the II Series of DR of December 16th, 2019; i3S Research Grants Regulation.
Place: The research activities will be hosted at i3S, under the scientific coordination of Professor Cristina Barrias.
Length time: The duration of the fellowship is 18 months, eventually renewable until 36 months. The expected starting date is july 2021. Monthly maintenance stipend: ?1.646,00, according to the values table of FCT, at Portugal (https://www.fct.pt/apoios/bolsas/docs/Tabela_Valores_SMM_LOE_2021.pdf). The payments will be made by bank transference. Research grants may also include other components, as the voluntary social insurance, under the terms of the Research Fellowship Holder Statute, article 10.
Evaluation Criteria: The selection will be based on the scientific merit and research capacity of the candidates and will encompass two stages: 1) curricular evaluation (total score 100%) through the analysis of the applicant´s CV (40%), research experience with relevance for the project work plan as described in the Admission Requirements (40%) and motivation letter (20%); 2) the most highly ranked candidates (up to 3) will be invited for an interview (final score: 50% curricular evaluation, 50% interview). The final classification system for candidates is expressed on a scale from 0 to 100.
Evaluation Pannel: President - Cristina Barrias, Pannel members: Ana Luísa Torres, Diana Nascimento and Sílvia Bidarra (substitute)
Information and Publicity of Funding Granted: The evaluation results will be published on the i3S website. The candidates will be notified by email. Candidates have a period of ten working days to, if they wish, to express their opinion at the prior hearing of the interested parties, by email [email protected].
Applications: The call will be open between 28th may to 14th june. The applications must be submitted electronically at:
https://dozer.i3s.up.pt/applicationmanagement/#/addapplications/Fellow_BIPDFCT_Proj2020i3S280514062021
The required documents composing the applications are: a) Copy of certificate or diploma; b) Detailed curriculum vitae, c) Letter of motivation in English, d) Reference Letter
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